Signalling index

Organised on the pathway taxonomy used by the major bioactive catalogues

Headings follow the public signalling-pathway index published by MedChemExpress — kinase families, epigenetic writers, peptides, probes and bench reagents — so a laboratory can move from a paper’s target to a stock code without learning a private taxonomy.

• 25 articlesPeptides & hormonesSignalling peptides, hormones and defined sequences, lyophilized and released against a peptide certificate.
• 44 articlesProtein tyrosine kinase / RTKEGFR, HER2, VEGFR, FGFR and related receptor-tyrosine-kinase tools.
• 21 articlesPI3K/Akt/mTORGrowth-factor signalling from the lipid kinase to the rapamycin-sensitive complex.
• 16 articlesMAPK/ERKRaf, MEK, ERK and the stress-activated MAP kinases.
• 13 articlesJAK/STATJanus kinases and the cytokine transcription factors they feed.
• 37 articlesCell cycle / DNA damageCyclin-dependent kinases, PARP, checkpoints and microtubule tools.
• 29 articlesEpigeneticsWriters, erasers and readers of chromatin marks, plus DNA-methylation tools.
• 8 articlesApoptosisBcl-2 family ligands, caspase tools and classical cytotoxic reference molecules.
• 7 articlesAutophagyLysosomal and mTOR-linked tools used to induce or block autophagic flux.
• 7 articlesProteostasisProteasome inhibitors and chemical chaperones.
• 4 articlesPROTACDegraders and E3-ligase ligands used in targeted-protein-degradation work.
• 35 articlesGPCR / G proteinSmall-molecule and peptide-adjacent ligands for G-protein-coupled receptors.
• 53 articlesNeuronal signalingTransmitters, amino-acid ligands and receptor tools for neuroscience.
• 22 articlesMembrane transporter / ion channelChannel blockers, transport inhibitors and membrane-potential tools.
• 39 articlesMetabolic enzyme / proteaseMetabolic enzymes, protease inhibitors and pathway metabolites.
• 34 articlesNuclear receptorSteroid, PPAR, FXR, LXR and related nuclear-receptor ligands.
• 20 articlesImmunology / inflammationCytokine-pathway and inflammatory-signalling tools.
• 10 articlesCytoskeletonActin- and tubulin-directed reference molecules.
• 13 articlesStem cell / WntWnt, Hedgehog, Notch and GSK-3 tools used in stem-cell work.
• 28 articlesAnti-infectionResearch antibiotics, antifungals and antiparasitic reference molecules.
• 54 articlesNatural productsPlant, microbial and marine metabolites held as defined chemical articles.
• 24 articlesFluorescent probesDyes and indicators for microscopy, viability and binding assays.
• 68 articlesBiochemical assay reagentsBuffers, reductants, cofactors, media supplements and electrophoresis reagents.
• 10 articlesReference proteinsResearch-grade proteins and reference antibodies. Not finished medicinal products.